| 发明名称 |
THIOKETALS AND THIOETHERS FOR INHIBITING THE EXPRESSION OF VCAM-1 |
| 摘要 |
Thioketals and thioethers are provided that inhibit the expression of VCAM-1 , and which can be used in the treatment of VCAM-1 mediated diseases including inflammatory disorders, cardiovascular diseases, occular diseases, autoimmun e diseases, neurological disorders, and cancer. The compounds also can be used to treat hyperlipidemia and/or hypercholesterolemia.
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| 申请公布号 |
CA2403823(A1) |
申请公布日期 |
2001.09.27 |
| 申请号 |
CA20012403823 |
申请日期 |
2001.03.21 |
| 申请人 |
ATHEROGENICS, INC. |
发明人 |
SOMERS, PATRICIA K.;MENG, CHARLES Q.;HOONG, LEE K.;SIKORSKI, JAMES A. |
| 分类号 |
C07D295/08;A61K31/10;A61K31/145;A61K31/166;A61K31/185;A61K31/192;A61K31/198;A61K31/401;A61K31/4164;A61K31/4402;A61K31/4406;A61K31/505;A61K31/5375;A61K31/662;A61K31/7034;A61K45/00;A61P1/00;A61P1/02;A61P3/04;A61P3/06;A61P3/10;A61P9/00;A61P9/10;A61P9/12;A61P11/02;A61P11/06;A61P11/08;A61P13/02;A61P13/12;A61P17/00;A61P17/02;A61P17/06;A61P17/14;A61P19/02;A61P25/00;A61P25/02;A61P25/16;A61P25/28;A61P27/02;A61P29/00;A61P35/00;A61P37/02;A61P37/08;A61P43/00;C07C323/20;C07C323/60;C07D207/16;C07D213/30;C07D233/64;C07D239/26;C07H15/203;(IPC1-7):C07C323/20;A61K31/70 |
主分类号 |
C07D295/08 |
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