| 发明名称 |
Antisense inhibition of MEKK2 expression |
| 摘要 |
Antisense compounds, compositions and methods are provided for modulating the expression of MEKK2. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding MEKK2. Methods of using these compounds for modulation of MEKK2 expression and for treatment of diseases associated with expression of MEKK2 are provided.
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| 申请公布号 |
US6287860(B1) |
申请公布日期 |
2001.09.11 |
| 申请号 |
US20000488744 |
申请日期 |
2000.01.20 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
MONIA BRETT P.;GAARDE WILLIAM;WARD DONNA T.;FREIER SUSAN M.;WYATT JACQUELINE |
| 分类号 |
C12N15/09;A61K31/7088;A61K31/7115;A61K31/712;A61K31/7125;A61K38/00;A61K48/00;A61P29/00;A61P35/00;C12N5/10;C12N15/113;(IPC1-7):A61K31/711;C07H21/00;C12N5/08 |
主分类号 |
C12N15/09 |
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