发明名称 |
Degradable heterobifunctional poly (ethylene glycol) acrylates and gels and conjugates derived therefrom |
摘要 |
A heterobifunctional poly(ethylene glycol) is provided having a hydrolytically degradable linkage, a first terminus comprising an acrylate group, and a second terminus comprising a target such as a protein or pharmaceutical agent or a reactive moiety capable of coupling to a target. Hydrogels can be prepared. The hydrogels can be used as a carrier for a protein or a pharmaceutical agent that can be readily released in a controlled fashion.
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申请公布号 |
US2001016624(A1) |
申请公布日期 |
2001.08.23 |
申请号 |
US20010824395 |
申请日期 |
2001.04.02 |
申请人 |
DEBIO RECHERCHE PHARMACEUTIQUE S.A. |
发明人 |
HARRIS J. MILTON;ZHAO XUAN |
分类号 |
A61K47/48;C08F299/00;C08G65/329;C08G81/00;(IPC1-7):C08H1/00;C08G65/00;C08L89/00;C08G65/32;C08F283/00;C08F283/06;A61K9/14;C07C33/025 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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