| 摘要 |
Novel scavenger receptors having an SR structure and a collectin-like structure which are proteins having the amino acid sequences of SEQ ID NOS:2 , 4 and 24 or proteins having comparable properties thereto, which are usable in clarifying the functions of macrophages and basal immunity, in clarifying th e onset mechanisms of various diseases such as arteriosclerosis, diabetic complications, re-constriction after angioplasty and bacterial infection, in diagnosing, preventing and treating these diseases and in developing reagent s and drugs therefor; and molecules related thereto such as derivatives or fragments thereof, isolated polynucleotides containing base sequences encodi ng the same, antibodies and antagonists. A treatment method by using these receptors is also disclosed.
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