A novel bioconjugate and a method for delivering the bioconjugate to a cell site is described. In particular, the bioconjugate composition comprises a targeting agent conjugated to a diagnostically or therapeutically effective agent by a metabolizable linker moiety which is cleaved by an exogenous enzyme.
申请公布号
WO0151091(A1)
申请公布日期
2001.07.19
申请号
WO2001US01153
申请日期
2001.01.11
申请人
FRED HUTCHINSON CANCER RESEARCH CENTER;UNIVERSITY OF WASHINGTON;BERNSTEIN, IRWIN, D.;SENTER, PETER, D.;BEESON, CRAIG, CANO;HART, MICHAEL
发明人
BERNSTEIN, IRWIN, D.;SENTER, PETER, D.;BEESON, CRAIG, CANO;HART, MICHAEL