| 发明名称 |
INHIBITORS OF INTEGRIN .ALPHA.V.BETA.3 |
| 摘要 |
The invention relates to novel compounds of formula (I) which are biological ly active as .alpha.v.beta.3 integrin ligands X-Y-Z-R1-CH2-R2(R4)-CH2-CO-R5, whereby X, Y, Z, R1, R2, R4 and R5 have meanings cited in Claim (1). The invention also relates to the physiologically acceptable salts and solvates thereof.
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| 申请公布号 |
CA2382561(A1) |
申请公布日期 |
2001.03.01 |
| 申请号 |
CA20002382561 |
申请日期 |
2000.08.04 |
| 申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG |
发明人 |
GOODMAN, SIMON;JONCZYK, ALFRED;SCHADT, OLIVER |
| 分类号 |
C07D233/48;A61K31/4164;A61K31/4168;A61K31/4184;A61K31/44;A61K31/4402;A61K31/505;A61P7/02;A61P9/10;A61P11/00;A61P13/12;A61P17/02;A61P17/06;A61P19/10;A61P27/02;A61P29/00;A61P31/00;A61P35/00;A61P43/00;C07D213/74;C07D233/60;C07D233/88;C07D235/30;C07D239/42;(IPC1-7):C07D213/74;C07D521/00;C07D409/12;A61K31/416;A61K31/418;A61K31/440;C07D333/48 |
主分类号 |
C07D233/48 |
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