| 摘要 |
<p>Methods of identifying a subject-specific, tissue-specific binding molecule in a human subject are provided. The method involves injecting a library of molecules into a human and identifying molecules which bind to a specific tissue. The binding molecule can be used to direct drugs to the specific tissue of the human to treat various diseases such as cancer. The method can also be used to direct an immunomodulatory molecule to a tissue to stimulate the production of a local immune response at the tissue. The methods are particularly advantageous in developing individualized therapies. The methods can also be used to detect cancer cells in a subject after treatment for cancer and preferably from a subject who has undergone surgery.</p> |
