发明名称 |
METHODS FOR CARBON-CENTERED RADICAL MEDIATED HEAVY HYDROGEN LABELING OF COMPOUNDS |
摘要 |
The solvent accessible reduced carbon atoms in a molecule of interest are labeled with heavy hydrogen. The carbon atoms are labeled under anaerobic, aqueous conditions by exposing the molecule of interest to a hydrogen atom abstractor in the presence of a heavy hydrogen source and a heavy hydrogen donor. If the hydrogen atom abstractor is hydroxyl radical, an electron scavenger source is provided. Optionally, an internal reference is provided to facilitate experimental reproducibility.
|
申请公布号 |
CA2376003(A1) |
申请公布日期 |
2000.12.07 |
申请号 |
CA20002376003 |
申请日期 |
2000.06.01 |
申请人 |
GOSHE, MICHAEL B.;ANDERSON, VERNON E. |
发明人 |
GOSHE, MICHAEL B.;ANDERSON, VERNON E. |
分类号 |
C07K1/13;(IPC1-7):C07K1/13 |
主分类号 |
C07K1/13 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|