MORPHOLINO-N-ETHYL ESTER DERIVATIVE OF AN INDOLE sPLA2 INHIBITOR
摘要
The compound, ((3-(2-amino-1,2-dioxoethyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl)ox y)acetic acid morpholino-N-ethyl ester, is disclosed together with its use as a highly bioavailable indole compound for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.
申请公布号
WO0069818(A1)
申请公布日期
2000.11.23
申请号
WO2000US06704
申请日期
2000.05.08
申请人
ELI LILLY AND COMPANY;BEIGHT, DOUGLAS, WADE;BUBEN, JOHN, ANDREW;MORIN, JOHN, MICHAEL, JUNIOR;SALL, DANIEL, JON;SAWYER, JASON, SCOTT
