| 摘要 |
The use of at least one oligosaccharide of the general formula (I), comprising 2 to 6 oside residues, and having a galactose residue in the non-reducing terminal position, or a derivative of such an oligosaccharide substituted by a hydrophobic residue, in the manufacture of a medicament wherein, (I) Galactose-n(alpha or beta)-(Hex)p, n is 1,2,3,4 or 6, Hex is and alpha or beta linked hexose or pentose, p is 1 to 5, and the derivative of said oligosaccharide being chosen in the following categories: a) glycosides corresponding to the formulae: (i) oligosaccharide 1-O-R, in which R is a linear or branched alkyl residue of 1 to 18 carbon atoms, (ii) oligosaccharide 1-O-R-O-1-oligosaccharide in which R is (CH2)m, in which m is between 2 and 10, b) an osylamine acylated according to one of the following formulae: (iii) oligosaccharide 1-NH-CO-R, in which R is an alkyl residue of 2 to 18 carbon atoms, containing 0, 1 or 2 double bonds, (iv) oligosaccharide 1-NH-CO-R-CO-NH-1-oligosaccharide, in which R is (CH2)m and m is between 2 and 8, c) an alkylamine acylated by an aldonic acid obtained by oxidation of an oligosaccharide: (v) oligosaccharide CO-NH-R, in which R has the same meaning as in formula (iii), (vi) oligosaccharide CO-NH-R-NH-CO-oligosaccharide, in which R has the same meaning as in formula (iii), d) a reduction product of Schiff bases formed by oligosaccharides with aliphatic mono or diamines, and corresponding to one of the following formulae: (vii) Gal-(Hex)n-X-HN-R, (viii) Gal-(Hex)n-X-HN-R-NH-X-(Hex)n-Gal, in which Hex is a hexose or pentose, n is 0, 1 or 2, X is 1-NH2-hexitol and R has the same meaning as in (iii). Also described is a dermatocosmetic composition which comprises at least one of the abovementioned active principals and a use of the composition in the cosmetic treatment of hyperactive skin.
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