Ginkgolides as inhibitors of membrane expression of benzodiazepine receptors to treat excess glucocorticoid production

摘要

The use of an essentially pure ginkgolide selected from ginkgolide A, B, C, J, M or analogue, the preferred compound being of the formula 1 for the manufacture of a medicament for inhibiting membrane expression of a benzodiazepene receptor and glucocorticoid release. Further disclosed is a pharmaceutical composition comprising the ginkgolide.