摘要 |
<p>A G protein-coupled receptor protein, peptide fragments thereof or salts of the same and polynucleotides (for example, DNA, RNA and derivatives thereof) encoding the same are useful: (1) in determining a ligand (an agonist); (2) in acquiring an antibody or an antiserum; (3) in constructing a recombinant receptor protein expression system; (4) in developing a receptor-bonded assay system and screening a candidate for a drug with the use of the above expression system; (5) in designing a drug based on a comparison with a ligand receptor having a similar structure; (6) as reagents for preparing a probe or a PCR primer in gene diagnosis; (7) in constructing a transgenic animal; (8) as drugs such as gene preventives and remedies; etc.</p> |