MANGANESE SUPEROXIDE DISMUTASE REGULATORY ELEMENTS AND USES THEREOF
摘要
A novel transcriptional regulatory element which was isolated from the MnSOD gene and which exhibits promoter-enhancer activity is disclosed. The promoter-enhancer activity of the element is further modulated by inflammatory mediators to regulate transcription. Methods of using the promoter-enhancer element to regulate gene expression, and therapeutic uses involving the promoter-enhancer element are also described.
申请公布号
WO0032801(A1)
申请公布日期
2000.06.08
申请号
WO1999US28331
申请日期
1999.11.30
申请人
UNIVERSITY OF FLORIDA;NICK, HARRY, S.;ROGERS, RICHARD;VALENTINE, JOHN, F.
发明人
NICK, HARRY, S.;ROGERS, RICHARD;VALENTINE, JOHN, F.