We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins and disclose methods and materials for using that procedure to regulatably initiate cell-specific apoptosis (programmed cell death) in genetically engineered cells.
申请公布号
US6054436(A)
申请公布日期
2000.04.25
申请号
US19980087811
申请日期
1998.05.29
申请人
BOARD OF TRUSTEES OF LELAND S. STANFORD JR. UNIV.;PRESIDENT & FELLOWS OF HARVARD COLLEGE
发明人
CRABTREE, GERALD R.;SCHREIBER, STUART L.;SPENCER, DAVID M.;WANDLESS, THOMAS J.;BELSHAW, PETER
