| 发明名称 |
STABLE SPRAY-DRIED PROTEIN FORMULATIONS |
| 摘要 |
Spray-dried particles having improved protein stability are produced by spray-drying a mixture including a protein, a phospholipid and an organic-aqueous co-solvent. Spray-dried particles which include at least 1 weight % phospholipid, having a tap density of less than 0.4 g/cm<3> can be prepared. The particles can be delivered to the pulmonary system of a patient.
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| 申请公布号 |
WO0010541(A1) |
申请公布日期 |
2000.03.02 |
| 申请号 |
WO1999US19306 |
申请日期 |
1999.08.25 |
| 申请人 |
ADVANCED INHALATION RESEARCH, INC. |
发明人 |
EDWARDS, DAVID, A.;HRKACH, JEFFREY, S. |
| 分类号 |
A61K9/12;A61K9/00;A61K9/14;A61K9/16;A61K9/72;A61K38/27;A61K47/02;A61K47/24;A61K49/00;A61P5/06;A61P11/00;A61P11/06;A61P43/00;B01J2/04;(IPC1-7):A61K9/72 |
主分类号 |
A61K9/12 |
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