Mature alveolar SP-B and a process for producing the same

摘要

Mature alveolar surfactant protein B and a process for producing the same is disclosed. The process includes the use of a fusion protein of SP-B having a propeptide only at its amino terminus. A propeptide at its carboxyl terminus is not necessary, and thus not included in the fusion protein, to produce the mature SP-B of this process. Cleavage of the amino-terminus propeptide results in the production of mature SP-B.