发明名称 NOVEL Z-VALACYCLOVIR CRYSTALS
摘要 <p>Crystals of 2-Ä(2-amino-1,6-dihydro-6-oxo-9H-purine-9-yl)methoxyÜethyl N-Ä(benzyloxy)carbonylÜ-L-valinate, having peaks at angles of diffraction of at least 15.3 DEG , 21.3 DEG , 23.8 DEG and 27.2 DEG (2&thetas;, CuK alpha rays) in the diffraction X-ray in the determination by the powder X-ray diffraction method, are provided. These catalysts are substantially not hygroscopic and have a high purity and a low impurity content and, therefore, useful as intermediates for Valaciclovir used as an antiviral drug.</p>
申请公布号 EP0976750(A1) 申请公布日期 2000.02.02
申请号 EP19980900380 申请日期 1998.01.16
申请人 AJINOMOTO CO., INC. 发明人 TAKEDA, HIDEO;KATAYAMA, SATOSHI;INEYAMA, TAKASHI;KISHISHITA, AKIHIRO;NAGASHIMA, KAZUTAKA
分类号 C07D473/00;(IPC1-7):C07D473/18 主分类号 C07D473/00
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