发明名称 |
HETEROAROMATIC QUINUCLIDINENES, THEIR USE AND PREPARATION |
摘要 |
The invention relates to novel compounds of general formula (I), wherein R is a group of general formula (II) or (III), where X1 represents oxygen or sulphur and Y1 and Z1 both represent carbon, or X1 represents oxygen and one of Y1 and Z1 represersts nitrogen and the other represents carbon, or X1 represents sulphur, Y1 represents nitrogen and Z1 represents carbon; one of X2, Y1 and Z2 represents oxygen or sulphur and the other two both represent carbon or one represents nitrogen and the other represents carbon, and the dotted line in formula (III) represents an optional additional carbon-carbon or carbon-nitrogen bond; A1, A2, A3 and A4 each represent carbon or, when one of X2, Y2 and Z2 represents oxygen or sulphur and the other two both represent carbon, one or two of A1, A2, A3 and A4 may represent nitrogen and the others carbon; and R1 to R5 are as defined in the description. The compounds of formula (I) can be used for treating diseases related to muscarininc receptor function.
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申请公布号 |
CA2135487(C) |
申请公布日期 |
1999.12.14 |
申请号 |
CA19932135487 |
申请日期 |
1993.05.11 |
申请人 |
GLAS, GUNILLA;HACKSELL, ULI;JOHANSSON, GARY;NILSSON, BJORN;NILVEBRANT, LISBETH;NORDVALL, GUNNAR;KABI PHARMACIA AB |
发明人 |
GLAS, GUNILLA;HACKSELL, ULI;JOHANSSON, GARY;NILSSON, BJORN;NILVEBRANT, LISBETH;NORDVALL, GUNNAR |
分类号 |
A61K31/435;A61P1/04;A61P1/06;A61P9/06;A61P13/00;A61P13/06;A61P25/00;A61P25/14;A61P25/16;A61P25/18;A61P25/20;A61P25/28;A61P27/06;C07D453/02;C07F7/22;(IPC1-7):C07D453/02;C07D519/00;A61K31/495 |
主分类号 |
A61K31/435 |
代理机构 |
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