| 发明名称 |
Water soluble rapamycin esters |
| 摘要 |
A compound of the structure wherein R1 and R2 are each, independently, hydrogen or -COCH2-S-CH2CH2-O-CH2-(CH2OCH2)n-CH2-O-CH2CH2-OCH3; and n=8-450; with the proviso that R1 and R2 are not both hydrogen, which is useful as an immunosuppressive, antiinflammatory, antifungal, antiproliferative, and antitumor agent.
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| 申请公布号 |
US5955457(A) |
申请公布日期 |
1999.09.21 |
| 申请号 |
US19980046043 |
申请日期 |
1998.03.23 |
| 申请人 |
AMERICAN HOME PRODUCTS CORPORATION |
发明人 |
LEE, HYUK-KOO;ZHU, TIANMIN |
| 分类号 |
A61K31/435;A61K31/436;A61K47/48;A61P11/00;A61P29/00;A61P31/04;A61P35/00;A61P37/00;A61P37/06;C07D498/16;C07D498/18;C08G65/329;(IPC1-7):A61K31/33 |
主分类号 |
A61K31/435 |
| 代理机构 |
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