发明名称 Stereoselective tc-99m ligands
摘要 The present invention concerns novel ligands, represented by Formulae (I), (II), (I') and (II'), that form complexes with a radioactive metal through a chelate bond. The complexes are useful in radiodiagnostic compositions employed for imaging. In said formulae, X, R<1> and R<2>, R<3> and R<4>, R<5> and R<6>, m and n are defined herein. The compounds of the invention avoid the formation of diastereomers based on incorporating [Tc<v>O]<+3>N2S2 as a chelating moiety since these compounds form only one isomer when complexed with [<99m>Tc][Tc<v>O]<+>.
申请公布号 AU4067899(A) 申请公布日期 1999.08.30
申请号 AU19990040678 申请日期 1999.02.05
申请人 TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 发明人 HANK F. KUNG;MEI-PING KUNG;ZHIPING ZHUANG
分类号 A61K51/04 主分类号 A61K51/04
代理机构 代理人
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