摘要 |
PROBLEM TO BE SOLVED: To obtain the subject substance useful as an active breeder agent for Bifidobacterium which activates the Bifidobacterium to improve breeding and settling the profitable Bifidobacterium and improves production efficiency in manufacturing medicines and foods including the Bifidobacterium by extracting from the lees of rice wine with an alcohol. SOLUTION: This substance is obtained as a compound having a molecular weight of <=5,000 and extracted from the lees of rice wine with an alcohol. The extractant alcohol is preferably ethanol. The objective substance is obtained by such a process that ethanol is added to the lees of rice wine to perform extraction, then the ethanol is distilled away from the extract and the resultant concentrate is treated in a separatory funnel, then the aqueous layer is evaporated to dryness. It is preferable to include 0.15-1.20% (weight ratio) objective substance in the 2nd objective active breeder agent for Bifidobacterium as the active ingredient. This substance imparts a peculiarly high growth- stimulative effect, acid resistance and drought resistance to Bifidobacterium, therefore the highly effective active breeder agent for Bifidobacterium is obtained. |