| 摘要 |
<p>Compounds of formula (I): wherein R is hydrogen, C1-10alkyl, C3-8cycloalkyl, C3-8cycloalkylC1-6alkyl, phenylC1-6alkyl or phenyl; R1 is C¿1-6?alkyl, C2-6alkenyl, C1-6alkoxy, halo, hydroxy, C1-6alkanoyl, haloC1-6alkyl, cyano or nitro; m is 0, 1 or 2; R?2¿ is C¿1-6?alkyl; n is 0, 1 or 2; are empomil inhibitors and are useful in the treatment of neurological disorders such as stroke, head trauma, transient cerebral ischemic attack, and chronic neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, diabetic neuropathy, amyotrophic lateral sclerosis, multiple sclerosis, vascular dementia and AIDS-related dementia.</p> |
