发明名称 HYDRATE OF 5-[4-[2- (N-METHYL-N- (2-PYRIDIL)AMINO) ETHOXY]BENZYL] THIAZOLIDINE-2, 4-DIONE MALEIC ACID SALT
摘要 A hydrate of 5-4-2- (N-methyl-N- (2-pyridyl)amino) ethoxy!benzyl! thiazolidine-2, 4-dione, maleic acid salt, characterised in that it: (i) comprises water in the range of from 0.2 to 1.1 % w/w; and (ii) provides an infrared spectrum containing peaks at 764 and 579 cm-1; and/or (iii) provides an X-ray powder diffraction (XRPD) pattern substantially as set out in Figure II; a process for the preparation of such a compound, a pharmaceutical composition containing such a compound and the use of such a compound or composition in medicine.
申请公布号 CA2314965(A1) 申请公布日期 1999.06.24
申请号 CA19982314965 申请日期 1998.12.14
申请人 SMITHKLINE BEECHAM P.L.C. 发明人 SASSE, MICHAEL JOHN;LEE, DAVID C.;BLACKLER, PAUL DAVID JAMES
分类号 A61K31/4427;A61K31/4439;A61P3/10;C07D417/12;(IPC1-7):C07D417/12;A61K31/425 主分类号 A61K31/4427
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