发明名称 |
HYDRATE OF 5-[4-[2- (N-METHYL-N- (2-PYRIDIL)AMINO) ETHOXY]BENZYL] THIAZOLIDINE-2, 4-DIONE MALEIC ACID SALT |
摘要 |
A hydrate of 5-4-2- (N-methyl-N- (2-pyridyl)amino) ethoxy!benzyl! thiazolidine-2, 4-dione, maleic acid salt, characterised in that it: (i) comprises water in the range of from 0.2 to 1.1 % w/w; and (ii) provides an infrared spectrum containing peaks at 764 and 579 cm-1; and/or (iii) provides an X-ray powder diffraction (XRPD) pattern substantially as set out in Figure II; a process for the preparation of such a compound, a pharmaceutical composition containing such a compound and the use of such a compound or composition in medicine.
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申请公布号 |
CA2314965(A1) |
申请公布日期 |
1999.06.24 |
申请号 |
CA19982314965 |
申请日期 |
1998.12.14 |
申请人 |
SMITHKLINE BEECHAM P.L.C. |
发明人 |
SASSE, MICHAEL JOHN;LEE, DAVID C.;BLACKLER, PAUL DAVID JAMES |
分类号 |
A61K31/4427;A61K31/4439;A61P3/10;C07D417/12;(IPC1-7):C07D417/12;A61K31/425 |
主分类号 |
A61K31/4427 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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