The present invention relates to a novel CK alpha -5 protein which is a member of the alpha chemokine family. In particular, isolated nucleic acid molecules are provided encoding the human CK alpha -5 protein. CK alpha -5 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of CK alpha -5 activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders.
申请公布号
WO9927078(A1)
申请公布日期
1999.06.03
申请号
WO1998US24619
申请日期
1998.11.18
申请人
HUMAN GENOME SCIENCES, INC.;WEI, YING-FEI;NI, JIAN;LI, YI;ROSEN, CRAIG, A.;RUBEN, STEVEN, M.
发明人
WEI, YING-FEI;NI, JIAN;LI, YI;ROSEN, CRAIG, A.;RUBEN, STEVEN, M.