发明名称 CRYSTALLINE ANTIFUNGAL POLYMORPH
摘要 The crystalline polymorph Form I of (-)-4-¢4- ¢4-¢4-¢ ¢(2R-cis)-5-(2, 4difluorophenyl) tetrahydro-5-(1H-1, 2,4-triazol- 1-ylmethyl)furan-3-yl! methoxy!phenyl! -1-piperazinyl! phenyl-2,4-dihydro-2- ¢(S)-1-ethyl-2(S)-hydroxylpropyl!-3H-1, 2,4-triazol-3-one represented by formula (I), pharmaceutical compositions containing such a polymorph and methods of using such a polymorph to treat fungal infections in mammals are disclosed.
申请公布号 CA2305803(A1) 申请公布日期 1999.04.15
申请号 CA19982305803 申请日期 1998.10.05
申请人 SCHERING CORPORATION 发明人 SUDHAKAR, ANANTHA R.;LEONG, WILLIAM;ANDREWS, DAVID R.
分类号 A61K31/4196;A61K31/496;A61K31/4965;A61P31/10;C07D241/00;C07D249/00;C07D307/00;C07D405/14;(IPC1-7):C07D405/14;A61K31/41;A61K31/495 主分类号 A61K31/4196
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