发明名称 STABILIZED PREPARATIONS FOR USE IN NEBULIZERS
摘要 Stabilized dispersions are provided for the delivery of a bioactive agent to the respiratory tract of a patient. The dispersions preferably comprise a stabilized colloidal system which may comprise a fluorochemical component. In particularly preferred embodiments, the stabilized dispersions comprises perforated microstructures dispersed in a fluorochemical suspension medium. As density variations between the suspended particles and suspension medium are minimized and attractive forces between microstructures are attenuated, the disclosed dispersions are particularly resistant to degradation, such as by settling or flocculation. In particularly preferred embodiments, the stabilized dispersions may be administered to the lung of a patient using a nebulizer.
申请公布号 WO9916420(A1) 申请公布日期 1999.04.08
申请号 WO1998US20603 申请日期 1998.09.29
申请人 ALLIANCE PHARMACEUTICAL CORP.;SCHUTT, ERNEST, G.;TARARA, THOMAS, E.;DELLAMARY, LUIS, A.;KABALNOV, ALEXEY;WEERS, JEFFRY, G. 发明人 SCHUTT, ERNEST, G.;TARARA, THOMAS, E.;DELLAMARY, LUIS, A.;KABALNOV, ALEXEY;WEERS, JEFFRY, G.
分类号 A61K9/00;A61K9/12;A61K9/16;A61K9/22;A61K9/51;A61K9/72;A61K45/00;A61K47/24;A61K49/04;A61P11/00;A61P39/00 主分类号 A61K9/00
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