发明名称 |
Process for preparing 4-fluoro-3-trifluoromethylphenol |
摘要 |
Disclosed is a process for preparing 4-fluoro-3-trifluoromethylphenol from 4-fluoro-3-trifluoromethylaniline, which comprises the steps of (1) using about 1 to 20 parts by weight of water based on 1 part by weight of 4-fluoro-3-trifluoromethylaniline in the presence of sulfuric acid to obtain 4-fluoro-3-trifluoromethylaniline sulfate; (2) subjecting the obtained 4-fluoro-3-trifluoromethylaniline sulfate to a diazotization reaction by using a diazotizing agent to obtain an aqueous solution containing about 8 to 25% by weight of a 4-fluoro-3-trifluoromethylbenzene-diazonium salt where a sulfuric acid concentration after diazotization is about 30 to 70% by weight in terms of the amount of sulfuric acid added, and the amount of water used is about 1 to 20 parts by weight based on 1 part by weight of 4-fluoro-3-trifluoromethylaniline; and (3) hydrolyzing the obtained 4-fluoro-3-trifluoromethylbenzenediazonium salt where a sulfuric acid concentration is about 30 to 70% by weight in terms of the amount of sulfuric acid added in a copper sulfate aqueous solution.
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申请公布号 |
US5892126(A) |
申请公布日期 |
1999.04.06 |
申请号 |
US19970969692 |
申请日期 |
1997.11.13 |
申请人 |
UBE INDUSTRIES, LTD. |
发明人 |
HARADA, KATSUMASA;MATSUSHITA, AKIO;KAWACHI, YASUHIRO |
分类号 |
C07C39/26;(IPC1-7):C07C39/24 |
主分类号 |
C07C39/26 |
代理机构 |
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代理人 |
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地址 |
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