New thiazolyl-alkadienol and -epoxide derivatives

摘要

Protected thiazolyl-alkadienol derivatives of formula (II) and thiazolyl-epoxide compounds of formula (VII) are new. R1 = 1-4C alkyl; R2 = chelate forming protecting group; R3 = H or 1-4C alkyl; Y = COOR4, CHO, CH=CH2 or CH2R5; R4 = 1-4C alkyl or optionally substituted benzyl; R5 = halo, OH, p-toluenesulphonate or -OSO2B; B = 1-4C alkyl or 1-4C perfluoroalkyl; in (VII) R1 can also be H if R2 = p-methoxybenzyl (PMB). Various new 1,3-dioxan derivative intermediates are also claimed.