发明名称 PROCESS FOR PREPARING OPTICALLY ACTIVE α-TRIFLUOROMETHYLLACTIC ACID AND ANTIPODE ESTERS THEREOF AND METHOD OF PURIFICATION THEREOF
摘要 <p>A process for preparing optically active α-trifluoromethyllactic acid and antipode esters thereof, characterized by asymmetrically hydrolyzing a racemic α-trifluoromethyllactic ester represented by formula (I) (wherein R represents a substituted or unsubstituted hydrocarbon group having 1 to 12 carbon atoms) in the presence of an enzyme, an immobilized enzyme, a microorganism, a cell culture, or a treated cell each having the capability of asymmetrically hydrolyzing the ester; and a method for purifying optically active α-trifluoromethyllactic acid, characterized by recrystallizing the optically active α-trifluoromethyllactic acid prepared by the above process or a racemic optically active α-trifluoromethyllactic acid prepared by hydrolyzing the racemic ester prepared by the above process and recovering the formed crystals.</p>
申请公布号 WO1999004028(P1) 申请公布日期 1999.01.28
申请号 JP1998003160 申请日期 1998.07.14
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