发明名称 |
TISSUE PLASMINOGEN ACTIVATOR-LIKE PROTEASE |
摘要 |
The present invention relates to a novel t-PALP protein which is a member of the serine protease family. In particular, isolated nucleic acid molecules are provided encoding the human t-PALP protein. t-PALP polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of t-PALP activity. Also provided are diagnostic methods for detecting circulatory system-related disorders and therapeutic methods for treating circulatory system-related disorders.
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申请公布号 |
CA2291482(A1) |
申请公布日期 |
1998.12.03 |
申请号 |
CA19982291482 |
申请日期 |
1998.05.27 |
申请人 |
HUMAN GENOME SCIENCES, INC. |
发明人 |
EBNER, REINHARD;MOORE, PAUL A.;RUBEN, STEVEN M. |
分类号 |
C12N15/09;A61K38/00;A61P7/02;A61P9/00;C12N1/21;C12N5/10;C12N9/64;C12N15/55;(IPC1-7):C12N15/55;C07H21/04;C12N15/63 |
主分类号 |
C12N15/09 |
代理机构 |
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地址 |
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