| 发明名称 |
QUINUCLIDINE DERIVATIVES |
| 摘要 |
Compounds of formula (1), wherein R1 is methoxy and R2 is selected from the grou p consisting of methyl, ethyl,isopropyil, sec-butyl and tert-butyl; and the pharmaceutically acceptable salts of such comp ounds. These compounds are substance P antagonists and useful in the treatment of gastrointestinal disorders, inflamm atory disorders, central nervous system disorders and pain.
|
| 申请公布号 |
CA2102179(C) |
申请公布日期 |
1998.10.27 |
| 申请号 |
CA19922102179 |
申请日期 |
1992.04.28 |
| 申请人 |
PFIZER INC. |
发明人 |
ITO, FUMITAKA;KONDO, HIROSHI;SHIMADA, KAORU;NAKANE, MASAMI;LOWE, JOHN A., III;ROSEN, TERRY J. |
| 分类号 |
C07D453/02;A01N43/90;A61K;A61K31/395;A61K31/435;A61K31/439;A61K31/44;A61K31/445;A61P1/00;A61P1/16;A61P11/00;A61P25/00;A61P25/04;A61P25/20;A61P25/24;A61P29/00;A61P43/00;C07D;C07D453/00;C07D453/04;C07D471/10;(IPC1-7):C07D453/02 |
主分类号 |
C07D453/02 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
