发明名称 |
HUMAN P24 VESICLE PROTEINS |
摘要 |
The present invention provides two human p24 vesicle trafficking proteins (designated individually as Hp24-1 and Hp24-2 and collectively as Hp24) and polynucleotides which identify and encode Hp24. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding Hp24 and a method for producing Hp24. The invention also provides for agonists, antibodies, or antagonists specifically binding Hp24, and their use, in the prevention and treatment of diseases associated with expression of Hp24. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding Hp24 for the treatment of diseases associated with the expression of Hp24. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding Hp24. |
申请公布号 |
WO9836068(A2) |
申请公布日期 |
1998.08.20 |
申请号 |
WO1998US02813 |
申请日期 |
1998.02.12 |
申请人 |
INCYTE PHARMACEUTICALS, INC.;GOLI, SURYA, K.;BANDMAN, OLGA |
发明人 |
GOLI, SURYA, K.;BANDMAN, OLGA |
分类号 |
C12N15/09;A61K38/00;A61K39/395;A61K45/00;A61P35/00;A61P43/00;C07K14/705;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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