发明名称 COMPOSES CONSTITUANT NOTAMMENT DES EFFECTEURS DE RECEPTEURS DU SYSTEME NERVEUX CENTRAL SENSIBLES AUX AMINO ACIDES NEUROEXCITATEURS, LEUR PREPARATION ET LEURS APPLICATIONS BIOLOGIQUES
摘要 The invention concerns compounds of formula (I) in which: R1 to R4, identical or different, represent hydrogen, alkyl or aryl, themselves substituted if required, R1 and R2 together further capable of representing a bridge -(CH2)m in which m is a whole number from 1 to 5, or a bridge X representing a linear combination of m hydrocarbon groups, m being as defined above and comprising, if required, at least a heteroatom such as O, N or S, or a bridge X representing a linear combination of p heteroatoms O, N and/or S, in which p is a whole number from 1 to 3; A1 and A2 represent -COOH, -SO3H or -PO3H2 radicals, or their derivatives such as esters or amides, or only one of A1 or A2 has these meanings, when R1 and R2 represent a single bond between the carbons in positions 3 and 4, the other of these groups being a hydrogen atom; Y represents a chain -(CH2)n-, n being zero or a whole number from 1 to 5, or represents a linear combination of n hydrocarbon groups and at least a heteroatom O, N or S, or a linear combination of q heteroatoms O, N and/or S, in which q is a whole number from 1 to 3. The invention is applicable as medicines.
申请公布号 FR2759366(A1) 申请公布日期 1998.08.14
申请号 FR19970001573 申请日期 1997.02.11
申请人 CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 发明人
分类号 A61P21/00;A61K31/198;A61P25/02;A61P25/16;A61P25/28;C07C229/48;(IPC1-7):C07C229/48;A61K31/195 主分类号 A61P21/00
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