| 发明名称 |
PROCESS FOR THE PREPARATION OF SUSTITUTED INDOLINONE DERIVATIVES |
| 摘要 |
A process which comprises reductive cyclisation of a compound of structure (II) <CHEM> in which n is 1 to 3 and X is a group displaceable by amine in the presence of at least two equivalents of anhydrous iron (III) chloride and at least two equivalents of an acetyl halide and a solvent to form a compound of structure (III) <CHEM> in which X and n are as hereinabove defined, Z is halogen. f |
| 申请公布号 |
KR0143088(B1) |
申请公布日期 |
1998.07.15 |
| 申请号 |
KR19880007283 |
申请日期 |
1988.06.17 |
| 申请人 |
SMITH KLINE & FRENCH LABORATORIES LIMITED |
发明人 |
FORTUNAK, JOSEPH M;GILES, ROBERT GORDON |
| 分类号 |
A61K31/40;C07C45/60;C07C45/85;C07C47/55;C07C67/00;C07C201/00;C07C205/00;C07C205/09;C07D209/34 |
主分类号 |
A61K31/40 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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