Amino acid derivatives and application thereof

摘要

There are disclosed amino acid derivatives represented by the following general formula (I): General formula (I) <IMAGE> wherein L1 and L2 represent an amino acid residue etc., A1 and A3 represent C=O, A2 represents an alkylene group etc., m and n represent an integer of 1 to 5, V represents -NHC(=NH)NH2 etc., W represents -COOH etc., R1 and R2 represent hydrogen atom, alkyl group etc., R3 and R4 represent hydrogen etc. and X and Y represent -NH- or -O- and pharmaceutically acceptable salts thereof and agents for inhibiting tumor matastasis containing the compounds, and the amino acid derivatives exhibit high activity for inhibiting tumor metastasis and weak platelet aggregation inhibition activity and weak anticoagulation activity.