Marker and immunological reagent for dialysis-related amyloidosis, diabetes mellitus and diabetes mellitus complications

摘要

An immunological reagent for diagnosis of or the evaluation of the effect of a medicine for dialysis-related amyloidosis, comprising an antibody which reacts specifically with a carboxymethylated alpha -amino acid, a carboxymethylated protein, or a carboxymethylated peptide; an immunological reagent for diagnosis of or the evaluation of the effect of a medicine for diabetes mellitus and diabetes mellitus complications, comprising an antibody which reacts specifically with an N< alpha >-carboxymethylated alpha -amino acid, an N< alpha >-carboxymethylated protein, or an N< alpha >-carboxymethylated peptide; a carboxymethylated alpha -amino acid, a carboxymethylated protein, or a carboxymethylated peptide as a marker for dialysis-related amyloidosis; or an N< alpha >-carboxymethylated alpha -amino acid, an N< alpha >-carboxymethylated protein, or an N< alpha >-carboxymethylated peptide as a marker for diabetes mellitus or diabetes mellitus complications.