| 摘要 |
Disclosed are a pyridazinone compound represented by the formula: <IMAGE> (I) wherein (1) R1 is a substituted or unsubstituted C1-10 alkyl, a C3-6 cycloalkyl, a lower alkenyl, a heterocyclic group having N, O or S atom or camphor-10-yl; R3 is hydrogen, a substituted or unsubstituted lower alkyl or a lower alkenyl; or R1 and R3 are bonded at terminal ends thereof to form a lower alkylene; and Z is a group represented by the formula: <IMAGE> where n is 1 or 2; and D is hydrogen or a halogen; or (2) R1 is a substituted or unsubstituted C1-10 alkyl, a substituted or unsubstituted phenyl, a C3-6 cycloalkyl, a lower alkenyl, a heterocyclic group having N, O or S atom or camphor-10-yl; R3 is hydrogen, a substituted or unsubstituted lower alkyl or a lower alkenyl; or R1 and R3 are bonded at terminal ends thereof to form a lower alkylene; and Z is a group represented by the formula: <IMAGE> and R2 is hydrogen, a substituted or unsubstituted lower alkyl, an aryl or a lower alkenyl; and -A-B- is an ethylene or vinylene each of which may be substituted by 1 or 2 groups selected from the group consisting of a lower alkyl and phenyl group, or a pharmaceutically acceptable salt thereof, and processes for preparing the same.
|
