发明名称 Biphenylsulfonamide matrix metalloproteinase inhibitors.
摘要 Compounds of formula (I) wherein R<1> includes alkyl, halo, nitro, amino, cyano, alkoxy, and alkoxycarbonyl; R<2> is alkyl and substituted alkyl; and R<3> is OH or NHOH, are useful for inhibiting matrix metalloproteinase enzymes in animals, and as such, prevent and treat diseases resulting from the breakdown of connective tissues.
申请公布号 ZA9704223(B) 申请公布日期 1997.12.10
申请号 ZA19970004223 申请日期 1997.05.15
申请人 WARNER-LAMBERT COMPANY 发明人 PATRICK MICHAEL O'BRIEN;DRAGO ROBERT SLISKOVIC
分类号 A61K31/18;A61K31/00;A61K31/195;A61K31/215;A61K31/216;A61P9/00;A61P9/10;A61P19/00;A61P19/02;A61P43/00;C07C311/19;C07C311/29;C07C311/37;C07C311/42 主分类号 A61K31/18
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