发明名称 |
Process for the preparation of alpha-ketocarbonic acid esters |
摘要 |
<p>Process for the preparation of E-oxime ethers of phenylglyoxylic acid esters of the general formula I …<IMAGE>… in which the variables have the following meanings: … … the substituents X and Y are selected from a group comprising halogen, C1-C4-alkyl, C1-C4-alkoxy or trifluoromethyl; … m is an integer from 0 to 4; … n is an integer from 0 to 3,… and in which … … a) a phenol of the general formula II …<IMAGE>… is converted into the phenolate, … b) the latter is mixed with a lactone of the general formula III …<IMAGE>… … c) the molten mixture is reacted, and … d) the resulting 2-phenoxymethylbenzoic acid of the general formula IV …<IMAGE>… is converted, via the acid chloride, into the benzoyl cyanide and this is converted into the corresponding alpha-keto acid, which is converted into the compound I. … … Alternatively, the compound IV can be converted, via the ester, into the beta-keto sulphoxide, which is reacted to give the beta-keto ester, which is subsequently converted into the compound I.</p> |
申请公布号 |
GR3024518(T3) |
申请公布日期 |
1997.11.28 |
申请号 |
GR19970402161T |
申请日期 |
1997.08.22 |
申请人 |
BASF AKTIENGESELLSCHAFT |
发明人 |
WINGERT, HORST, DR.;WOLF, BERND, DR.;BENOIT, REMY, DR.;SAUTER, HUBERT, DR.;HEPP, MICHAEL, DR.;GRAMMENOS, WASSILIOS, DR.;KUEKENHOEHNER, THOMAS, DR. |
分类号 |
C07C69/736;C07C;C07C51/09;C07C51/367;C07C59/68;C07C65/21;C07C65/24;C07C67/22;C07C69/738;C07C69/76;C07C235/34;C07C235/78;C07C249/08;C07C251/48;C07C253/14;C07C255/17;C07C255/40;C07C317/24;(IPC1-7):C07C69/738 |
主分类号 |
C07C69/736 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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