LIQUID CHROMATOGRAPHY COLUMN

摘要

A chromatography cartridge assembly (12) includes a cartridge (22) with flexible wall defining a chamber, and porous, polymeric, hydrophilic, chromatography media contained within the chamber. The chromatography media have an operating pressure greater than 3 bars. The flexible wall has a moving diaphragm for compressing the chromatography media. The chromatography cartridge assembly (12) includes a flow distributor, flow collector, and sieves formed from a hydrophilic material. A compression module (20) defines a pressure chamber for containing a pressurized fluid. The pressurized fluid acts to move the flexible wall of the cartridge assembly (12). The compression module (20) has a pressure rating greater than 3 bars.