发明名称 |
Method for assessing sensitivity of tumor cells to cephalomannine and 10-deacetyltaxol |
摘要 |
A method for assessing the sensitivity of a patient's tumor cells to cephalomannine and 10-deacetyltaxol in order to treat those tumor cells involves the removal of a sample of the tumor cells and establishing a cell line therefrom. Cells from the cell line are cultured and then contacted with varying concentrations of cephalomannine or 10-deacetyltaxol to form treated cells. The treated cells are assessed to determine the cytotoxic effect of the cephalomannine and/or the 10-deacetyltaxol and, where cytotoxic response is exhibited, a therapeutic dosage is formulated using the selected concentration of cephalomannine or 10-deacetyltaxol and a carrier material. The method is particularly useful for neural and glial tumor cells.
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申请公布号 |
US5688517(A) |
申请公布日期 |
1997.11.18 |
申请号 |
US19930010821 |
申请日期 |
1993.01.29 |
申请人 |
NAPRO BIOTHERAPEUTICS, INC. |
发明人 |
HELSON, LAWRENCE;AINSWORTH, STERLING K. |
分类号 |
G01N33/50;(IPC1-7):A61F13/00 |
主分类号 |
G01N33/50 |
代理机构 |
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