发明名称 |
Iodinated paramagnetic chelates, and their use as contrast agents |
摘要 |
PCT No. PCT/EP94/01677 Sec. 371 Date May 30, 1995 Sec. 102(e) Date May 30, 1995 PCT Filed May 25, 1994 PCT Pub. No. WO94/27644 PCT Pub. Date Dec. 8, 1994Novel compounds containing a polyiodinated aromatic or heteroaromatic residue and their chelate complexes with ions of metal elements with atomic number from 20 to 31, 39, from 42 to 44, 49 and from 57 to 83, and their salts with physiologically tolerable organic and inorganic bases are useful contrast agents for preparation of diagnostic formulations to obtain images of organs and/or tissues of human and animal body through the use of nuclear magnetic resonance or X-rays or the combination of both nuclear magnetic resonance and X-rays.
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申请公布号 |
US5660814(A) |
申请公布日期 |
1997.08.26 |
申请号 |
US19950448476 |
申请日期 |
1995.05.30 |
申请人 |
DIBRA S.P.A. |
发明人 |
UGGERI, FULVIO;ANELLI, PIER LUCIO;FEDELI, FRANCO;MURRU, MARCELLA;DE HAEN, CHRISTOPH |
分类号 |
C07D257/02;A61K49/00;A61K49/04;A61K49/08;A61K51/00;A61K51/04;C07C237/04;C07C237/10;(IPC1-7):A61K49/00;G01N31/00;G01N33/48 |
主分类号 |
C07D257/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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