发明名称 |
Antiviral naphthoquinone compounds, compositions and uses thereof |
摘要 |
The present invention provides novel antiviral naphthoquinone compounds, which may be isolated from plants of the genus Conospermum or synthesized chemically, in accordance with the present inventive methods. The antiviral naphthoquionone compounds, derivatives thereof, and prodrugs thereof, may be used alone or in combination with other antiviral agents in compositions, such as pharmaceutical compositions, to inhibit the growth or replication of a virus, such as a retrovirus, in particular a human immunodeficiency virus, specifically HIV-1 or HIV-2, in the treatment or prevention of viral infection. |
申请公布号 |
AU680872(B2) |
申请公布日期 |
1997.08.14 |
申请号 |
AU19940060991 |
申请日期 |
1994.01.31 |
申请人 |
THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEP |
发明人 |
MICHAEL R. BOYD;JOHN H. CARDELLINA II;KIRK R GUSTAFSON;LAURENT A DECOSTERD;IAN PARSONS;LEWIS PANNEL;JAMES B. MCMAHON;GORDON M CRAGG |
分类号 |
C07D211/46;A61K31/00;A61K31/12;A61K31/35;A61K31/352;A61K31/37;A61K31/505;A61K31/52;A61K31/70;A61K38/00;A61K38/17;A61K38/21;A61K45/06;A61P31/00;A61P31/12;A61P31/18;C07C46/00;C07C46/10;C07C50/32;C07D311/46;C07D311/54;C07D311/56;C07D311/92;(IPC1-7):C07D311/92 |
主分类号 |
C07D211/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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