METHOD FOR DETECTING NONA-NONE HEPATITIS ASSOCIATED VIRUS NUCLEOTIDE SEQUENCES PEPTIDES, AND COMPOSITIONS

摘要

Method to detect specific nucleic acids of nonA-nonE hepatitis associated virus in a sample comprising the following steps: to put in contact in conditions allowing the hybridisation a GBV-C specific oligonucleotide probe either with said nucleic acids, or with amplified nucleic acids thereof, so that a nucleic acid-probe complex is formed, said probe comprising a nucleotide sequence substantially complementary to a sequence fragment of said nucleic acids, or of amplified nucleic acids thereof; to selectively detect said complex. Said nucleic acid were detected in patients suffering of nonA-nonE hepatitis but also of other pathologies, as autoimmune diseases, aplastic anaemia, haematology diseases, etc.