摘要 |
<p>A compound represented by general formula (I-2) or a pharmaceutically acceptable acid-addition salt thereof, useful as a anti-microbial against Helicobacter pylori and as a medicinal composition for treating Helicobacter pylori infection, wherein Ar represents phenyl, biphenyl or naphthyl each having at least one substituent selected from the group consisting of halogeno, cyano, nitro, carboxy, C1-C18 alkyl, C1-C18 alkoxy, C3-C18 cycloalkyl, C7-C18 aralkyl, C8-C18 arylalkenyl, C7-C18 aralkyloxy, optionally substitued phenoxy, optionally substituted C2-C19 alkoxycarbonyl, and optionally substituted C2-C19 aralkyloxycarbonyl, provided the case where Ar represents phenyl substituted by halogeno, cyano nitro, carboxy, C1-C18 alkyl, optionally substituted C2-C19 alkoxycarbonyl or C2-C19 aralkyloxycarbonyl is expected.</p> |