| 摘要 |
PROBLEM TO BE SOLVED: To obtain the subject stabilizing agent containing calcium gluconate, giving an extremely stable preparation and useful for the stabilization of oily physiologically active substances such as fish oil containing docosahexaenoic acid. SOLUTION: This stabilizing agent contains (A) calcium gluconate and preferably further (B) an agent for forming a reticulate matrix, or contains the component A, the component B and (C) a fixing agent. The component B is e.g. milk calcium, milk casein or their hydrolyzate and the component C is preferably starch, dextrin, etc. The stabilizing preparation can be prepared by mixing the component B, an emulsifying agent, etc., into purified water, adding an oily physiologically active substance to the mixture, adding the component A and the component C thereto, subjecting the obtained mixture to vigorous agitation treatment or passing through a high-pressure homogenizer and drying and pulverizing the product. The amounts of the components A, B and C in the preparation are preferably 50-90wt.%, 1-20wt.% and about 0.2wt.%, respectively. |
