| 摘要 |
<p>The present invention is directed to an ophthalmic composition in the form of a topical aqueous solution consisting essentially of: an ophthalmologically active agent, an ion sensitive, hydrophilic polymer in an amount of 0.004 to 1.5 percent by weight, at least one salt selected from the group of inorganic salts and buffers in a total amount of from 0.01 to 2.0 percent by weight, a wetting agent in an amount of 0 to 3.0 percent by weight, a preservative in an amount of 0 to 0.02 percent by weight, water, and optionally a pH regulating agent in an amount sufficient to give a pH of 4.0 to 8.0 to the composition, the ratio between salt and polymer components being such that the solution exhibits a viscosity of less than 1000 mPas. The composition contains a sufficient amount of polymer to provide for a controlled absorption of the drug into the eye, its viscosity having been reduced to provide for better handling characteristics.</p> |
