METHOD OF ACTIVATING A NOVEL LIGAND REGULATORY PATHWAY

摘要

A novel ligand regulatory pathway is disclosed and methods of activating the novel pathway in a cell expressing a ligand for an Eph subfamily receptor tyrosine kinase protein. Methods are provided for identifying substances capable of activating the ligand regulatory pathway. Therapeutic methods for affecting neuronal development and regeneration and pharmaceutical compositions using the substances and Eph subfamily receptor tyrosine kinase proteins are also described.