发明名称 |
REDUCTION OF INTRAVENOUSLY ADMINISTERED NANOPARTICULATE-FORMULATION-INDUCED ADVERSE PHYSIOLOGICAL REACTIONS |
摘要 |
Disclosed are methods of intravenous administration of nanoparticulate drug formulations to a mammal to avoid adverse hemodynamic effects: by reducing the rate and concentration of the nanoparticles in the formulations; or by pretreating the subject with histamine; or by pretreating the subject with a desensitizing amount of the nanoparticulate drug formulations. |
申请公布号 |
WO9711686(A1) |
申请公布日期 |
1997.04.03 |
申请号 |
WO1996US15300 |
申请日期 |
1996.09.25 |
申请人 |
NANOSYSTEMS L.L.C. |
发明人 |
DE GARAVILLA, LAWRENCE;LIVERSIDGE, ELAINE, M.;LIVERSIDGE, GARY, G. |
分类号 |
A61K9/16;A61K9/127;A61K9/14;A61K45/06;A61K49/04;A61K49/18;(IPC1-7):A61K9/50;A61K47/30 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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