| 摘要 |
PURPOSE: To obtain a suppressant for carcinogenesis, containing a crude drug selected from Rhei Rhizoma, Gardenia Fructus, Coptidis Rhizome and Scutellariae Radix as an active ingredient, having great effects especially on prevention of onset of carcinoma of the colon and expectable great effects by administering to a patient, etc., suffering from the familial carcinoma of the colon. CONSTITUTION: This suppressant for carcinogenesis contains a crude drug selected from Rhei Rhizoma, Gardenia Fructus, Coptidis Rhizoma and Scutellariae Radix as an active ingredient. A Chinese medicinal formulation prepared by combining the crude drugs is preferably used as the crude drug. For example, SANOSHASHIN-TO (containing the Rhei Rhizoma, the Scutellariae Radix, the Coptidis Rhizoma, etc.), ORENGEDOKU-TO (containing the Coptidis Rhizoma, Phellondendri Cortex, the Scutellariae Radix, the Gardenia Fructus, etc.), TOKAKUJYOKI-TO (containing Pruni Persicae Semen, Cinnamomi Cortex, the Rhei Rhizoma, Glycyrrhizae Radix, etc.), SAIKOKARYUKOTSUBOREI-TO (containing Bupleuri Radix, Pinnelliae Tuber, Hoelen, Cinnamomi Cortex, the Scutellariae Radix, Zingiberis Rhizoma, the Rhei Rhizoma, etc.) and DAISAIKO-TO (Bupleuri Radix, Pinnelliae Tuber, Zingiberis Rhizoma, the Scutellariae Radix, the Rhei Rhizoma, etc.) are cited as the Chinese medicinal formu1ation. The objective medicine can mainly and perorally be administered. The daily dose thereof for an adult is preferably 0.5-30g exprgssed in terms of the Rhei Rhizoma used alone, 0.5-50g expressed in terms of the Gardenia Fructus used alone, 0.25-45g expressed in terms of the Coptidis Rhizoma used alone and 1-50g expressed in terms of the Scutellariae Radix used alone. When the Chinese medicinal formulation, e.g. the SANOSHASHIN-TO is used, the dose thereof may be 0.1-50g. |
